Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.1.1.76 extracted from

  • Terao, Y.; Ijima, Y.; Kakidani, H.; Ohta, H.
    Enzymatic synthesis of (R)-flurbiprofen (2003), Bull. Chem. Soc. JPN, 76, 2395-2397.
No PubMed abstract available

Application

Application Comment Organism
synthesis synthesis of the anti-cancer drug (R)-flurbiprofen Bordetella bronchiseptica

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Bordetella bronchiseptica

Organism

Organism UniProt Comment Textmining
Bordetella bronchiseptica
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant AMDase Bordetella bronchiseptica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-(2-fluoro-4-biphenyl)-2-methylmalonate
-
Bordetella bronchiseptica (R)-alpha-methyl-alpha-(2-fluoro-4-biphenyl)propionate + CO2 trivial name (R)flurbiprofen, 92% enantiomeric excess ?

Synonyms

Synonyms Comment Organism
AMDase
-
Bordetella bronchiseptica