Literature summary for 4.1.1.76 extracted from
Terao, Y.; Ijima, Y.; Kakidani, H.; Ohta, H.
Enzymatic synthesis of (R)-flurbiprofen (2003), Bull. Chem. Soc. JPN, 76, 2395-2397.
No PubMed abstract available
Application
Application |
Comment |
Organism |
synthesis |
synthesis of the anti-cancer drug (R)-flurbiprofen |
Bordetella bronchiseptica |
Cloned(Commentary)
Cloned (Comment) |
Organism |
expression in Escherichia coli |
Bordetella bronchiseptica |
Organism
Organism |
UniProt |
Comment |
Textmining |
Bordetella bronchiseptica |
- |
- |
- |
Purification (Commentary)
Purification (Comment) |
Organism |
recombinant AMDase |
Bordetella bronchiseptica |
Substrates and Products (Substrate)
Substrates |
Comment Substrates |
Organism |
Products |
Comment (Products) |
Rev. |
Reac. |
2-(2-fluoro-4-biphenyl)-2-methylmalonate |
- |
Bordetella bronchiseptica |
(R)-alpha-methyl-alpha-(2-fluoro-4-biphenyl)propionate + CO2 |
trivial name (R)flurbiprofen, 92% enantiomeric excess |
? |
|
Synonyms
Synonyms |
Comment |
Organism |
AMDase |
- |
Bordetella bronchiseptica |