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Literature summary for 4.1.1.64 extracted from
- 3,3,3-Trifluoro-2-aminoisobutyrate: a mechanism-based inhibitor of Pseudomonas cepacia alpha-dialkylamino acid (1979), Biochem. Biophys. Res. Commun., 90, 1104-1110.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 3,3,3-Trifluoro-2-aminoisobutanoate | irreversible, the inhibitor undergoes catalytic decarboxylation during the inactivation process and binds at the enzyme's active site | Burkholderia cepacia |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Burkholderia cepacia | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-Aminoisobutanoate + pyruvate | - |
Burkholderia cepacia | L-Ala + acetone + CO2 | - |
? | |
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Release 2023.1 (January 2023)
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