Literature summary for 4.1.1.50 extracted from

Lu, Z.J.; Markham, G.D.
Metal ion activation of S-adenosylmethionine decarboxylase reflects cation charge density (2007), Biochemistry, 46, 8172-8180.

Search for more literature for 4.1.1.50

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Al3+	activation, no significant influence on the rate-limiting step. Km value 0.850 mM	Escherichia coli
Ca2+	activation, no significant influence on the rate-limiting step. Km value 0.117 mM	Escherichia coli
Co2+	activation, no significant influence on the rate-limiting step. Km value 0.286 mM	Escherichia coli
Eu3+	activation, no significant influence on the rate-limiting step. Km value 0.095 mM	Escherichia coli
Fe2+	activation, no significant influence on the rate-limiting step. Km value 0.121 mM	Escherichia coli
Fe3+	activation, no significant influence on the rate-limiting step. Km value 0.194 mM	Escherichia coli
Gd3+	activation, no significant influence on the rate-limiting step. Km value 0.043 mM	Escherichia coli
Li+	activation, no significant influence on the rate-limiting step. Km value 0.219 mM	Escherichia coli
Mg2+	activation, no significant influence on the rate-limiting step. Km value 0.106 mM	Escherichia coli
Mn2+	activation, no significant influence on the rate-limiting step. Km value 0.045 mM	Escherichia coli
Tb3+	activation, no significant influence on the rate-limiting step. Km value 0.151 mM	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Reaction

Reaction	Comment	Organism	Reaction ID
S-adenosyl-L-methionine = S-adenosyl 3-(methylsulfanyl)propylamine + CO2	allosteric metal ion activation	Escherichia coli	a

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)