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Literature summary for 4.1.1.50 extracted from

  • Li, Y.F.; Hess, S.; Pannell, L.K.; Tabor, C.W.; Tabor, H.
    In vivo mechanism-based inactivation of S-adenosylmethionine decarboxylases from Escherichia coli, Salmonella typhimurium, and Saccharomyces cerevisiae (2001), Proc. Natl. Acad. Sci. USA, 98, 10578-10583.
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Escherichia coli
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 recombinant enzyme
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Saccharomyces cerevisiae P21182 recombinant enzyme, expression in Escherichia coli
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Salmonella enterica subsp. enterica serovar Typhimurium
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 recombinant enzyme, expression in Escherichia coli
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Posttranslational Modification

Posttranslational Modification Comment Organism
side-chain modification alkylation of a Cys residue, mechanism-based suicide inactivation Salmonella enterica subsp. enterica serovar Typhimurium
side-chain modification alkylation of a Cys residue, mechanism-based suicide inactivation Saccharomyces cerevisiae
side-chain modification alkylation of Cys140, mechanism-based suicide inactivation Escherichia coli