Literature summary for 4.1.1.49 extracted from

Sudom, A.; Walters, R.; Pastushok, L.; Goldie, D.; Prasad, L.; Delbaere, L.T.J.; Goldie, H.
Mechanisms of activation of phosphoenolpyruvate carboxykinase from Escherichia coli by Ca2+ and of desensitization by trypsin (2003), J. Bacteriol., 185, 4233-4242.

Search for more literature for 4.1.1.49

Cloned(Commentary)

Cloned (Comment)	Organism
-	Escherichia coli

Crystallization (Commentary)

Crystallization (Comment)	Organism
crystals grown by hanging drop vapor diffusion, monoclinic space group C2, unit cell parameter a = 126.2 A, b = 95.2 A, c = 46.8 A, d = 95.2 A	Escherichia coli

Protein Variants

Protein Variants	Comment	Organism
D269E	site-specific mutagenesis	Escherichia coli
deltaF409	site-specific mutagenesis, deletion of Phe409	Escherichia coli
E508Q/E511Q	site-specific mutagenesis	Escherichia coli
F409A	site-specific mutagenesis	Escherichia coli
F413A	site-specific mutagenesis	Escherichia coli
R2S	site-specific mutagenesis	Escherichia coli
R396S	site-specific mutagenesis	Escherichia coli
R396TAA	site-specific mutagenesis, termination codon at position 396	Escherichia coli

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Ca2+	activation	Escherichia coli
Mn2+	activation	Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + oxaloacetate	Escherichia coli	-	ADP + phosphoenolpyruvate + CO2	-	r

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Escherichia coli

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + oxaloacetate	-	Escherichia coli	ADP + phosphoenolpyruvate + CO2	-	r

Synonyms

Synonyms	Comment	Organism
PCK	-	Escherichia coli
phosphoenolpyruvate carboxykinase	-	Escherichia coli
phosphoenolpyruvate carboxykinase [ATP]	-	Escherichia coli

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Release 2023.1 (January 2023)