Literature summary for 4.1.1.45 extracted from

Egashira, Y.; Murotani, G.; Tanabe, A.; Saito, K.; Uehara, K.; Morise, A.; Sato, M.; Sanada, H.
Differential effects of dietary fatty acids on rat liver alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase activity and gene expression (2004), Biochim. Biophys. Acta, 1686, 118-124.

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Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Rattus norvegicus	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
additional information	-	ACMSD assay at pH 7.0 and in 50 mM potassium phosphate buffer. ACMSD activity is suppressed 20fold and 4fold after feeding of rats with linoleic acid concentrations of 20% and 10% respectively compared to 40 micromol/h/g protein without feeding of linoleic acid. Palmitic acid, stearic acid and oleic acid do not suppress ACMSD activity. N-3 fatty acids suppress ACMSD activity even at only 2% in diets.	Rattus norvegicus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate	-	Rattus norvegicus	2-aminomuconate-6-semialdehyde + CO2	-	?

Synonyms

Synonyms	Comment	Organism
ACMSD	-	Rattus norvegicus
alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase	-	Rattus norvegicus

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Release 2023.1 (January 2023)