Literature summary for 4.1.1.45 extracted from

Nishizuka, Y.; Ichiyama, A.; Hayaishi, O.
II. Picolinic carboxylase (cat liver) (alpha-amino-beta-carboxymuconic-epsilon-semialdehyde beta-decarboxylase) (1970), Methods Enzymol., 17A, 471-476.

No PubMed abstract available

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Inhibitors

Inhibitors	Comment	Organism	Structure
CuSO4	-	Felis catus
EDTA	-	Felis catus
HgCl2	-	Felis catus
NaF	-	Felis catus
PCMB	inhibition is prevented by either reduced glutathione or caseine	Felis catus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.001	-	2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate	-	Felis catus

Metals/Ions

Metals/Ions	Comment	Organism	Structure
MgCl2	slightly stimulates	Felis catus

Organism

Organism	UniProt	Comment	Textmining
Felis catus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Felis catus

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Felis catus	-

Storage Stability

Storage Stability	Organism
-20°C, stable for several months	Felis catus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate	-	Felis catus	2-aminomuconate semialdehyde + CO2	-	?

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
6	9.5	-	Felis catus

pH Stability

pH Stability	pH Stability Maximum	Comment	Organism
6	9.5	stable	Felis catus

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Release 2023.1 (January 2023)