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Literature summary for 4.1.1.37 extracted from
- Purification and properties of uroporphyrinogen decarboxylase from Saccharomyces cerevisiae (1990), Eur. J. Biochem., 188, 393-403.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5,5'-dithiobis(2-nitrobenzoate) | - |
Saccharomyces cerevisiae |  |
| Cu2+ | - |
Saccharomyces cerevisiae | |
| Fe2+ | - |
Saccharomyces cerevisiae | |
| Fe3+ | - |
Saccharomyces cerevisiae | |
| PCMB | - |
Saccharomyces cerevisiae | |
| Zn2+ | - |
Saccharomyces cerevisiae | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.000006 | - |
uroporphyrinogen III | - |
Saccharomyces cerevisiae | |
| 0.000007 | - |
7-COOH-porphyrinogen I | - |
Saccharomyces cerevisiae | |
| 0.00001 | - |
Uroporphyrinogen I | - |
Saccharomyces cerevisiae | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 38000 | - |
1 * 38000, SDS-PAGE | Saccharomyces cerevisiae |
| 46000 | - |
gel filtration | Saccharomyces cerevisiae |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Saccharomyces cerevisiae |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.029 | - |
- |
Saccharomyces cerevisiae |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -20°C, stable for several months | Saccharomyces cerevisiae |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 7-COOH-porphyrinogen I | - |
Saccharomyces cerevisiae | Coproporphyrinogen I + CO2 | - |
? | |
| uroporphyrinogen I | - |
Saccharomyces cerevisiae | coproporphyrinogen I + 4 CO2 | - |
? | |
| Uroporphyrinogen III | - |
Saccharomyces cerevisiae | Coproporphyrinogen III + 4 CO2 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 38000, SDS-PAGE | Saccharomyces cerevisiae |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5.7 | - |
uroporphyrinogen I, uroporphyrinogen III or 7-COOH-porphyrinogen I, estimation by coproporphyrinogen formation | Saccharomyces cerevisiae |
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Release 2023.1 (January 2023)
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