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Literature summary for 4.1.1.36 extracted from

  • Hernandez-Acosta, P.; Schmid, D.G.; Jung, G.; Culianez-Macia, F.A.; Kupke, T.
    Molecular characterization of the Arabidopsis thaliana flavoprotein AtHAL3a reveals the general reaction mechanism of 4'-phosphopantothenoylcysteine decarboxylases (2002), J. Biol. Chem., 277, 20490-20498.
    View publication on PubMed
Search for more literature for 4.1.1.36

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21 (DE3) Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
A174S site-directed mutagenesis Arabidopsis thaliana
A174V site-directed mutagenesis Arabidopsis thaliana
C175S site-directed mutagenesis Arabidopsis thaliana
D177N site-directed mutagenesis Arabidopsis thaliana
G179A site-directed mutagenesis Arabidopsis thaliana
R95Q site-directed mutagenesis Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
D-pantothenoylcysteine Arabidopsis thaliana pantothenoylaminoethenethiol is the intermediate in decarboxylation pantotheine + CO2
-
 ?
N-[(R)-4'-phosphopantothenoyl]-L-cysteine Arabidopsis thaliana key step in coenzyme A biosynthesis pantotheine 4'-phosphate + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant enzyme Arabidopsis thaliana

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-pantothenoylcysteine pantothenoylaminoethenethiol is the intermediate in decarboxylation Arabidopsis thaliana pantotheine + CO2
-
 ?
N-[(R)-4'-phosphopantothenoyl]-L-cysteine
-
 Arabidopsis thaliana pantotheine 4'-phosphate + CO2
-
 ?
N-[(R)-4'-phosphopantothenoyl]-L-cysteine key step in coenzyme A biosynthesis Arabidopsis thaliana pantotheine 4'-phosphate + CO2
-
 ?

Subunits

Subunits Comment Organism
trimer
-
 Arabidopsis thaliana

Synonyms

Synonyms Comment Organism
AtHAL3a
-
 Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
flavin flavoprotein Arabidopsis thaliana