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Literature summary for 4.1.1.35 extracted from

  • Simkhada, D.; Oh, T.J.; Pageni, B.B.; Lee, H.C.; Liou, K.; Sohng, J.K.
    Characterization of CalS9 in the biosynthesis of UDP-xylose and the production of xylosyl-attached hybrid compound (2009), Appl. Microbiol. Biotechnol., 83, 885-895.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli BL21 (DE3), the deoxysugar biosynthesis of Streptomyces sp. KCTC 0041BP is inactivated by gene replacement to generate Streptomyces sp. GerSM2 mutant, which is unable to produce dihydrochalcomycin, calS9 UDP-xylose biosynthetic genes are cloned in an integrative plasmid pSET152 to generate pBPDS, which is heterologously expressed in Streptomyces sp. GerSM2. A glycosylated product, a 5-O-xylosyl-chalconolide derivative, in the conjugal transformants is isolated Micromonospora echinospora subsp. calichensis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
33000
-
SDS-PAGE Micromonospora echinospora subsp. calichensis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
UDP-D-glucuronate Micromonospora echinospora subsp. calichensis
-
UDP-D-xylose + CO2
-
?

Organism

Organism UniProt Comment Textmining
Micromonospora echinospora subsp. calichensis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Micromonospora echinospora subsp. calichensis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
UDP-D-glucuronate
-
Micromonospora echinospora subsp. calichensis UDP-D-xylose + CO2
-
?

Synonyms

Synonyms Comment Organism
UDP-GlcA decarboxylase
-
Micromonospora echinospora subsp. calichensis

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Micromonospora echinospora subsp. calichensis