Literature summary for 4.1.1.33 extracted from

Vannice, J.C.; Skaff, D.A.; Keightley, A.; Addo, J.K.; Wyckoff, G.J.; Miziorko, H.M.
Identification in Haloferax volcanii of phosphomevalonate decarboxylase and isopentenyl phosphate kinase as catalysts of the terminal enzyme reactions in an archaeal alternate mevalonate pathway (2014), J. Bacteriol., 196, 1055-1063.

Search for more literature for 4.1.1.33

Inhibitors

Inhibitors	Comment	Organism	Structure
6-fluoromevalonate diphosphate	negligible inhibition	Haloferax volcanii
6-fluoromevalonate monophosphate	strong inhibition	Haloferax volcanii

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
ATP + (R)-5-diphosphomevalonate	Haloferax volcanii	-	ADP + phosphate + isopentenyl diphosphate + CO2	-	?

Organism

Organism	UniProt	Comment	Textmining
Haloferax volcanii	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
ATP + (R)-5-diphosphomevalonate	-	Haloferax volcanii	ADP + phosphate + isopentenyl diphosphate + CO2	-	?

Synonyms

Synonyms	Comment	Organism
phosphomevalonate decarboxylase	-	Haloferax volcanii
PMD	-	Haloferax volcanii

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)