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Literature summary for 4.1.1.33 extracted from

  • Nishimura, H.; Azami, Y.; Miyagawa, M.; Hashimoto, C.; Yoshimura, T.; Hemmi, H.
    Biochemical evidence supporting the presence of the classical mevalonate pathway in the thermoacidophilic archaeon Sulfolobus solfataricus (2013), J. Biochem., 153, 415-420.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Saccharolobus solfataricus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
37000
-
x * 37000, calculated Saccharolobus solfataricus
37028
-
x * 37028, calculated from sequence Saccharolobus solfataricus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ATP + (R)-5-diphosphomevalonate Saccharolobus solfataricus the enzyme catalyzes a reaction of the classical mevalonate pathway ADP + phosphate + isopentenyl diphosphate + CO2
-
?
ATP + (R)-5-diphosphomevalonate Saccharolobus solfataricus P2 the enzyme catalyzes a reaction of the classical mevalonate pathway ADP + phosphate + isopentenyl diphosphate + CO2
-
?
ATP + (R)-5-diphosphomevalonate Saccharolobus solfataricus DSM 1617 the enzyme catalyzes a reaction of the classical mevalonate pathway ADP + phosphate + isopentenyl diphosphate + CO2
-
?

Organism

Organism UniProt Comment Textmining
Saccharolobus solfataricus Q97UL5
-
-
Saccharolobus solfataricus DSM 1617 Q97UL5
-
-
Saccharolobus solfataricus P2 Q97UL5
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ATP + (R)-5-diphosphomevalonate
-
Saccharolobus solfataricus ADP + phosphate + isopentenyl diphosphate + CO2
-
?
ATP + (R)-5-diphosphomevalonate the enzyme catalyzes a reaction of the classical mevalonate pathway Saccharolobus solfataricus ADP + phosphate + isopentenyl diphosphate + CO2
-
?
ATP + (R)-5-diphosphomevalonate
-
Saccharolobus solfataricus P2 ADP + phosphate + isopentenyl diphosphate + CO2
-
?
ATP + (R)-5-diphosphomevalonate the enzyme catalyzes a reaction of the classical mevalonate pathway Saccharolobus solfataricus P2 ADP + phosphate + isopentenyl diphosphate + CO2
-
?
ATP + (R)-5-diphosphomevalonate
-
Saccharolobus solfataricus DSM 1617 ADP + phosphate + isopentenyl diphosphate + CO2
-
?
ATP + (R)-5-diphosphomevalonate the enzyme catalyzes a reaction of the classical mevalonate pathway Saccharolobus solfataricus DSM 1617 ADP + phosphate + isopentenyl diphosphate + CO2
-
?
additional information no substrate: mevalonate 5-phosphate Saccharolobus solfataricus ?
-
?
additional information no substrate: mevalonate 5-phosphate Saccharolobus solfataricus P2 ?
-
?
additional information no substrate: mevalonate 5-phosphate Saccharolobus solfataricus DSM 1617 ?
-
?

Subunits

Subunits Comment Organism
? x * 37000, calculated Saccharolobus solfataricus
? x * 37028, calculated from sequence Saccharolobus solfataricus

Synonyms

Synonyms Comment Organism
DMD
-
Saccharolobus solfataricus
SSO2989
-
Saccharolobus solfataricus
SSO2989 locus name Saccharolobus solfataricus

General Information

General Information Comment Organism
metabolism the enzyme catalyzes a reaction of the classical mevalonate pathway Saccharolobus solfataricus