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Literature summary for 4.1.1.31 extracted from

  • Paulus, J.K.; Foerster, K.; Groth, G.
    Direct and selective small-molecule inhibition of photosynthetic PEP carboxylase: New approach to combat C4 weeds in arable crops (2014), FEBS Lett., 588, 2101-2106.
    View publication on PubMed
Search for more literature for 4.1.1.31

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli strains BL21(DE) and BL21-Gold(DE) Flaveria pringlei
expressed in Escherichia coli strains BL21(DE) and BL21-Gold(DE) Flaveria trinervia

Inhibitors

Inhibitors Comment Organism Structure
(+)-catechin
-
 Flaveria pringlei
(+)-catechin
-
 Flaveria trinervia
2-(4-methoxyphenyl)-3-phenyl-quinoxaline
-
 Flaveria trinervia
AG 1433 i.e. 2-(3,4-dihydroxyphenyl)-6,7-dimethylquinoxaline Flaveria pringlei
AG 1433 i.e. 2-(3,4-dihydroxyphenyl)-6,7-dimethylquinoxaline Flaveria trinervia
epigallocatechin gallate
-
 Flaveria pringlei
epigallocatechin gallate
-
 Flaveria trinervia
additional information not inhibited by 2-(4-methoxyphenyl)-3-phenyl-quinoxaline Flaveria pringlei

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phosphate + oxaloacetate Flaveria pringlei
-
 phosphoenolpyruvate + HCO3-
-
 ?
phosphate + oxaloacetate Flaveria trinervia
-
 phosphoenolpyruvate + HCO3-
-
 ?

Organism

Organism UniProt Comment Textmining
Flaveria pringlei Q01647
-
-
Flaveria trinervia P30694
-
-

Purification (Commentary)

Purification (Comment) Organism
His-Trap FF or HP column chromatography Flaveria pringlei
His-Trap FF or HP column chromatography Flaveria trinervia

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphate + oxaloacetate
-
 Flaveria pringlei phosphoenolpyruvate + HCO3-
-
 ?
phosphate + oxaloacetate
-
 Flaveria trinervia phosphoenolpyruvate + HCO3-
-
 ?

Synonyms

Synonyms Comment Organism
PEP carboxylase
-
 Flaveria pringlei
PEP carboxylase
-
 Flaveria trinervia
PEPC
-
 Flaveria pringlei
PEPC
-
 Flaveria trinervia

Cofactor

Cofactor Comment Organism Structure
acetyl-CoA
-
 Flaveria pringlei
acetyl-CoA
-
 Flaveria trinervia

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.039
-
 at pH 8.0 and 25°C Flaveria trinervia AG 1433
0.065
-
 at pH 8.0 and 25°C Flaveria trinervia 2-(4-methoxyphenyl)-3-phenyl-quinoxaline
0.103
-
 at pH 8.0 and 25°C Flaveria trinervia (+)-catechin
0.307
-
 at pH 8.0 and 25°C Flaveria pringlei (+)-catechin