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Literature summary for 4.1.1.28 extracted from

  • Arakane, Y.; Lomakin, J.; Beeman, R.W.; Muthukrishnan, S.; Gehrke, S.H.; Kanost, M.R.; Kramer, K.J.
    Molecular and functional analyses of amino acid decarboxylases involved in cuticle tanning in Tribolium castaneum (2009), J. Biol. Chem., 284, 16584-16594.
    View publication on PubMedView publication on EuropePMC
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Dopa Tribolium castaneum
-
 dopamine + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Tribolium castaneum A7U8C8 red flour beetle
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Dopa
-
 Tribolium castaneum dopamine + CO2
-
 ?

Synonyms

Synonyms Comment Organism
3,4-Dihydroxyphenylalanine decarboxylase
-
 Tribolium castaneum
DDC
-
 Tribolium castaneum

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Tribolium castaneum

General Information

General Information Comment Organism
physiological function DDC is involved in the Tribolium cuticle sclerotization and pigmentation pathway, and is a candidate for the gene that is mutated in black Tribolium castaneum