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Literature summary for 4.1.1.28 extracted from

  • Bratland, E.; Wolff, A.S.; Haavik, J.; Kaempe, O.; Skoeldberg, F.; Perheentupa, J.; Bredholt, G.; Knappskog, P.M.; Husebye, E.S.
    Epitope mapping of human aromatic L-amino acid decarboxylase (2007), Biochem. Biophys. Res. Commun., 353, 692-698.
    View publication on PubMed
Search for more literature for 4.1.1.28

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli XL-1 Blue cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
E227A/R228A/D229A/K230A replacement of amino acids 227-230 (ERDK) with alanine residues reduces reactivity to 13.6% compared to the wild type enzyme Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
serum
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,4-Dihydroxyphenylalanine
-
 Homo sapiens Dopamine + CO2
-
 ?
5-hydroxy-L-tryptophan
-
 Homo sapiens serotonin + CO2
-
 ?

Synonyms

Synonyms Comment Organism
AADC
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate dependent Homo sapiens