Any feedback?
Literature summary for 4.1.1.28 extracted from
- Cloning and expression of human placental L-Dopa decarboxylase (2003), Neurochem. Res., 28, 797-803.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| cDNA, alternative mRNA splice variants, neuronal and nonneuronal | Homo sapiens |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.13 | - |
L-Dopa | pH 8.0, 37°C | Homo sapiens |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 50000 | - |
2 * 50000, SDS-PAGE | Homo sapiens |
| 54000 | - |
recombinant enzyme, immunoblotting | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-tryptophan | Homo sapiens | - |
tryptamine + CO2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
human | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| recombinant enzyme | Homo sapiens |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
specific activity 490 U/mg, enzyme activity is expressed in nanomole of substrate transformed per minute per milliliter of enzyme preparation | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Dopa | - |
Homo sapiens | dopamine + CO2 | - |
? | |
| L-tryptophan | - |
Homo sapiens | tryptamine + CO2 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homodimer | 2 * 50000, SDS-PAGE | Homo sapiens |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Aromatic L-amino acid decarboxylase | - |
Homo sapiens |
| DDC | - |
Homo sapiens |
| L-3,4-Dihydroxyphenylalanine decarboxylase | - |
Homo sapiens |
| L-DOPA decarboxylase | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Homo sapiens | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
