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Literature summary for 4.1.1.28 extracted from

  • Sumi, C.; Ichinose, H.; Nagatsu, T.
    Characterization of recombinant human aromatic L-amino acid decarboxylase expressed in COS cells (1990), J. Neurochem., 55, 1075-1078.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in COS cells Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.016
-
5-hydroxytryptophan
-
Homo sapiens
0.074
-
3,4-dihydroxyphenylalanine
-
Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3,4-Dihydroxyphenylalanine
-
Homo sapiens 3-Hydroxytyramine + CO2
-
?
5-Hydroxytryptophan
-
Homo sapiens Serotonin + CO2
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
3,4-dihydroxyphenylalanine as substrate Homo sapiens
7 8.4 5-hydroxytryptophan as substrate Homo sapiens

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate enhances activity Homo sapiens