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Literature summary for 4.1.1.25 extracted from
- Elicitor-induced L-tyrosine decarboxylase from plant cell suspension cultures (1988), Plant Physiol., 88, 52-55.
General Stability
| General Stability | Organism |
|---|---|
| stabilized in presence of pyridoxal 5'-phosphate | Thalictrum rugosum |
| stabilized in presence of pyridoxal 5'-phosphate | Eschscholzia californica |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| alpha-Difluoromethyltyrosine | weak | Eschscholzia californica |  |
| alpha-Fluoromethyl(3,4-dihydroxyphenyl)alanine | weak | Eschscholzia californica | |
| L-alpha-Aminooxy-beta-phenylpropionate | - |
Eschscholzia californica | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.24 | - |
L-3,4-dihydroxyphenylalanine | - |
Thalictrum rugosum | |
| 0.25 | - |
L-Tyr | - |
Eschscholzia californica | |
| 0.27 | - |
L-Tyr | - |
Thalictrum rugosum | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 56300 | - |
2 * 56300, SDS-PAGE | Thalictrum rugosum |
| 56300 | - |
2 * 56300, SDS-PAGE | Eschscholzia californica |
| 90000 | - |
native PAGE | Thalictrum rugosum |
| 90000 | - |
native PAGE | Eschscholzia californica |
| 95000 | - |
gel filtration | Thalictrum rugosum |
| 95000 | - |
gel filtration | Eschscholzia californica |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Eschscholzia californica | - |
- |
- |
| Thalictrum rugosum | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Thalictrum rugosum |
- |
Eschscholzia californica |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cell culture | - |
Thalictrum rugosum | - |
| cell culture | - |
Eschscholzia californica | - |
| cell suspension culture | - |
Thalictrum rugosum | - |
| cell suspension culture | - |
Eschscholzia californica | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-3,4-Dihydroxyphenylalanine | at 74% of the activity with L-Tyr | Thalictrum rugosum | Dopamine + CO2 | - |
? | |
| L-Tyr | - |
Thalictrum rugosum | Tyramine + CO2 | - |
? | |
| L-Tyr | - |
Eschscholzia californica | Tyramine + CO2 | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 56300, SDS-PAGE | Thalictrum rugosum |
| dimer | 2 * 56300, SDS-PAGE | Eschscholzia californica |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.4 | - |
- |
Thalictrum rugosum |
| 8.4 | - |
- |
Eschscholzia californica |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 7 | 9 | pH 7: about 30% of maximal activity, pH 9: about 50% of maximal activity | Thalictrum rugosum |
| 7 | 9 | pH 7: about 30% of maximal activity, pH 9: about 50% of maximal activity | Eschscholzia californica |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | the enzyme is dependent on exogenously supplied pyridoxal 5'-phosphate | Thalictrum rugosum | |
| pyridoxal 5'-phosphate | the enzyme is dependent on exogenously supplied pyridoxal 5'-phosphate | Eschscholzia californica | |
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Release 2023.1 (January 2023)
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