Literature summary for 4.1.1.22 extracted from

Moya-Garcia, A.A.; Ruiz-Pernia, J.; Marti, S.; Sanchez-Jimenez, F.; Tunon, I.
Analysis of the decarboxylation step in mammalian histidine decarboxylase. A computational study (2008), J. Biol. Chem., 283, 12393-12401.

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Protein Variants

Protein Variants	Comment	Organism
D271E	mutant conserves 2% of the wild type HDC activity	Rattus norvegicus
H197G	mutant retains 10% of the wild type HDC activity	Rattus norvegicus

Organism

Organism	UniProt	Comment	Textmining
Rattus norvegicus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-histidine	-	Rattus norvegicus	histamine + CO2	-	?

Synonyms

Synonyms	Comment	Organism
HDC	-	Rattus norvegicus

Cofactor

Cofactor	Comment	Organism	Structure
pyridoxal 5'-phosphate	-	Rattus norvegicus

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Release 2023.1 (January 2023)