Literature summary for 4.1.1.22 extracted from

de las Rivas, B.; Rodriguez, H.; Carrascosa, A.V.; Munoz, R.
Molecular cloning and functional characterization of a histidine decarboxylase from Staphylococcus capitis (2008), J. Appl. Microbiol., 104, 194-203.

Search for more literature for 4.1.1.22

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli JM109 (DE3) cells	Staphylococcus capitis

Protein Variants

Protein Variants	Comment	Organism
G58N	the amino acid change can be responsible for the slow autoactivation and the appearance of HDC in the pi chain form	Staphylococcus capitis

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
34200	-	pi chain of HDC	Staphylococcus capitis

Organism

Organism	UniProt	Comment	Textmining
Staphylococcus capitis	A9IZZ1	-	-
Staphylococcus capitis IFIJ12	A9IZZ1	-	-

Purification (Commentary)

Purification (Comment)	Organism
His-Trap-FF crude chelating affinity chromatography	Staphylococcus capitis

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-histidine	-	Staphylococcus capitis	histamine + CO2	-	?
L-histidine	-	Staphylococcus capitis IFIJ12	histamine + CO2	-	?

Synonyms

Synonyms	Comment	Organism
HDC	-	Staphylococcus capitis

Cofactor

Cofactor	Comment	Organism	Structure
pyridoxal 5'-phosphate	-	Staphylococcus capitis

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Release 2023.1 (January 2023)