Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
strain C57BL/6 resistant to infection by Leishmania major, and strain BALB/c susceptible to infection with Leishmania major | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lymph node | in the acute phase of infection of mice infected with Leishmania major, detected in both strains the resistant C57BL/6 and the susceptible BALB/c. Only susceptible mice known to be unable to control parasite dissemination show induction of histidine decarboxylase in their distant periaortic lymph nodes as well. During the chronic phase of infection only the heavily parasitized organs of BALB/c mice show high expression of histidine decarboxylase gene | Mus musculus | - |
mast cell | during the chronic phase of infection elevated levels of histidine decarboxylase, possibly of mast cell origin, are associated with Th2-dominated responses and serious disease development | Mus musculus | - |