Literature summary for 4.1.1.2 extracted from

da Silva, L.F.; Dias, C.V.; Cidade, L.C.; Mendes, J.S.; Pirovani, C.P.; Alvim, F.C.; Pereira, G.A.; Aragao, F.J.; Cascardo, J.C.; Costa, M.G.
Expression of an oxalate decarboxylase impairs the necrotic effect induced by Nep1-like protein (NLP) of Moniliophthora perniciosa in transgenic tobacco (2011), Mol. Plant Microbe Interact., 24, 839-848.

Application

Application	Comment	Organism
agriculture	the enzyme represents a potentially source of resistance against oxalate- and Nep1-like protein-producing pathogens such as Moniliophthora perniciosa, the causal agent of witches' broom disease of cacao, Theobroma cacao	Flammulina velutipes

Cloned(Commentary)

Cloned (Comment)	Organism
transgenic overexpressionin Nicotiana tabacum plants. The transgenic plants contain less oxalic acid and more formic acid compared with the control plants and show enhanced resistance to cell death induced by exogenous oxalate and MpNEP2, a Nep1-like protein of the hemibiotrophic fungus Moniliophthora perniciosa. inhibition of reactive oxygen species formation in the transgenic plants inoculated with oxalate, MpNEP2, or a combination of both programmed cell death elicitors	Flammulina velutipes

Cloned (Comment)

Organism

transgenic overexpressionin Nicotiana tabacum plants. The transgenic plants contain less oxalic acid and more formic acid compared with the control plants and show enhanced resistance to cell death induced by exogenous oxalate and MpNEP2, a Nep1-like protein of the hemibiotrophic fungus Moniliophthora perniciosa. inhibition of reactive oxygen species formation in the transgenic plants inoculated with oxalate, MpNEP2, or a combination of both programmed cell death elicitors

Flammulina velutipes

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
oxalate + H+	Flammulina velutipes	-	formate + CO2	-	?

Organism

Organism	UniProt	Comment	Textmining
Flammulina velutipes	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
oxalate + H+	-	Flammulina velutipes	formate + CO2	-	?

Synonyms

Synonyms	Comment	Organism
FvOXDC	-	Flammulina velutipes

General Information

General Information	Comment	Organism
additional information	the enzyme is involved in resistance against oxalate- and Nep1-like protein-producing pathogens in plants. Oxalic acid and Nep1-like proteins are recognized as elicitors of programmed cell death in plants, which is crucial for the pathogenic success of necrotrophic plant pathogens and involves reactive oxygen species	Flammulina velutipes