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Literature summary for 4.1.1.19 extracted from
- Role of arginine decarboxylase (ADC) in Arabidopsis thaliana defence against the pathogenic bacterium Pseudomonas viridiflava (2015), Plant Biol., 17, 831-839 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene ADC1, quantitative real-time PCR isozyme expression analysis | Arabidopsis thaliana |
| gene ADC2, quantitative real-time PCR isozyme expression analysis | Arabidopsis thaliana |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| additional information | construction of an ADC1 null mutant by T-DNA insertion. As opposed to wild-type plants, bacterial infection with Pseudomonas viridiflava strain Pvalb8 increases ADC2 expression and ADC activity in adc1 mutants, which can counterbalance the lack of ADC1. ADC1 expression in adc2-3 mutants is similar to wild-type plants, and ADC2 expression in adc1-3 mutants is also similar to wild-type plants | Arabidopsis thaliana |
| additional information | construction of an ADC2 null mutant by T-DNA insertion. ADC1 expression in adc2-3 mutants is similar to wild-type plants, and ADC2 expression in adc1-3 mutants is also similar to wild-type plants | Arabidopsis thaliana |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-arginine | Arabidopsis thaliana | - |
agmatine + CO2 | - |
? |  |
| L-arginine | Arabidopsis thaliana Col-0 | - |
agmatine + CO2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arabidopsis thaliana | O23141 | - |
- |
| Arabidopsis thaliana | Q9SI64 | - |
- |
| Arabidopsis thaliana Col-0 | O23141 | - |
- |
| Arabidopsis thaliana Col-0 | Q9SI64 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leaf | - |
Arabidopsis thaliana | - |
| additional information | in non-infected wild-type plants, isozyme ADC2 expression is much higher than ADC1 expression. ADC2 expression is strongly associated with seed germination, root and leaf development | Arabidopsis thaliana | - |
| additional information | the ADC1 promoter activity is low during vegetative development. In non-infected wild-type plants, isozyme ADC2 expression is much higher than ADC1 expression | Arabidopsis thaliana | - |
| root | - |
Arabidopsis thaliana | - |
| seed | - |
Arabidopsis thaliana | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-arginine | - |
Arabidopsis thaliana | agmatine + CO2 | - |
? | |
| L-arginine | - |
Arabidopsis thaliana Col-0 | agmatine + CO2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ADC | - |
Arabidopsis thaliana |
| ADC1 | - |
Arabidopsis thaliana |
| ADC2 | - |
Arabidopsis thaliana |
| ATADC1 | - |
Arabidopsis thaliana |
| AtADC2 | - |
Arabidopsis thaliana |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Arabidopsis thaliana |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
assay at | Arabidopsis thaliana |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Arabidopsis thaliana | |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Arabidopsis thaliana | as opposed to wild-type plants, bacterial infection with Pseudomonas viridiflava strain Pvalb8 increases ADC2 expression and ADC activity in adc1 mutants, which can counterbalance the lack of ADC1. High osmolarity, drought, salinity and wounding induce ADC2 expression. In non-inoculated adc mutants, the lack of each ADC isoform has no effect on expression of the other isoforms. Infection of the adc2-3 mutant also caused a several fold increase in ADC1 expression at both times after inoculation | up |
| Arabidopsis thaliana | bacterial infection induces putrescine accumulation and ADC1 expression in wild-type plants, but pathogen-induced putrescine accumulation is blocked in adc1 mutant. In non-inoculated adc mutants, the lack of each ADC isoform has no effect on expression of the other isoforms. Infection of the adc2-3 mutant also causes a several fold increase in ADC1 expression at both times after inoculation | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| malfunction | adc2 mutants show increased basal expression of salicylic acid and jasmonic acid-dependent PR genes. Simultaneous knockout of both AtADC genes leads to a lethal phenotype. Pseudomonas viridiflava strain Pvalb8 does not affect ADC activity of wild-type plants, but causes a 50% decrease in ADC activity of adc1-3 mutants. In contrast, Pseudomonas viridiflava strain Pvalb8 infection enhances ADC activity of adc2-3 1.3fold. The lack of a functional ADC1 or ADC2 gene does not affect Pseudomonas viridiflava propagation in Arabidopsis thaliana plants. Altered free and conjugated polyamine levels of wild-type Col-0 Arabidopsis thaliana and adc mutants in response to Pseudomonas viridiflava infection, overview | Arabidopsis thaliana |
| malfunction | pathogen-induced putrescine accumulation is blocked in adc1 mutants. Simultaneous knockout of both AtADC genes leads to a lethal phenotype. Pseudomonas viridiflava strain Pvalb8 does not affect ADC activity of wild-type plants, but causes a 50% decrease in ADC activity of adc1-3 mutants. In contrast, Pseudomonas viridiflava strain Pvalb8 infection enhances ADC activity of adc2-3 1.3fold. The lack of a functional ADC1 or ADC2 gene does not affect Pseudomonas viridiflava propagation in Arabidopsis thaliana plants. Altered free and conjugated polyamine levels of wild-type Col-0 Arabidopsis thaliana and adc mutants in response to Pseudomonas viridiflava infection, overview | Arabidopsis thaliana |
| physiological function | in Arabidopsis thaliana, putrescine is synthesised exclusively by arginine decarboxylase (ADC) catalyzing decarboxylation of arginine. Arginine decarboxylase exists as two isoforms (ADC1 and 2) that are differentially regulated by abiotic stimuli and that play a role in defence against pathogens and participate in Arabidopsis defence against Pseudomonas viridiflava. ADC2 contributes to a much higher extent than ADC1 to basal ADC activity and putrescine biosynthesis | Arabidopsis thaliana |
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