Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 4.1.1.19 extracted from

  • Moon, S.U.; Kwon, K.H.; Kim, J.H.; Bokara, K.K.; Park, K.A.; Lee, W.T.; Lee, J.E.
    Recombinant hexahistidine arginine decarboxylase (hisADC) induced endogenous agmatine synthesis during stress (2010), Mol. Cell. Biochem., 345, 53-60.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
the hexahistidine tagged human ADC gene is delivered into mouse fibroblast cell line (NIH3T3) using retroviral vector and transfected into the PT-67 cell line Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q96A70
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-arginine
-
Homo sapiens agmatine + CO2
-
?

Synonyms

Synonyms Comment Organism
ADC
-
Homo sapiens

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
Homo sapiens

General Information

General Information Comment Organism
physiological function higher level of hexahistidine tagged human ADC transgene expression completely trigger the endogenous agmatine synthesis during H2O2 injury thus protecting NIH3T3 cells against cytotoxicity Homo sapiens