General Stability | Organism |
---|---|
freeze-thawing or lyophilization completely inactivates | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | IC50: 0.8 mM | Rattus norvegicus | |
Co2+ | - |
Rattus norvegicus | |
additional information | no inhibition by DL-alpha-difluoromethylornithine | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.75 | - |
L-Arg | pH 8.0, 30°C | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrial membrane | most activity is associated with | Rattus norvegicus | 31966 | - |
additional information | no activity in cytosol | Rattus norvegicus | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | about 5% of the activity in aorta | Rattus norvegicus | - |
aorta | highest activity of all tissues tested | Rattus norvegicus | - |
brain | about 40% of the activity in aorta | Rattus norvegicus | - |
intestine | about 40% of the activity in aorta | Rattus norvegicus | - |
kidney | about 85% of the activity in aorta | Rattus norvegicus | - |
liver | about 75% of the activity in aorta | Rattus norvegicus | - |
stomach | about 60% of the activity in aorta | Rattus norvegicus | - |
testis | about 15% of the activity in aorta | Rattus norvegicus | - |
Storage Stability | Organism |
---|---|
4°C, 50% loss of activity after overnight storage of membrane suspension | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine | - |
Rattus norvegicus | agmatine + CO2 | - |
? | |
L-Orn | - |
Rattus norvegicus | Putrescine + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADC | - |
Rattus norvegicus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
25 | - |
- |
Rattus norvegicus |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
20 | - |
4 h, 80% loss of activity in mitochondrial/synaptosomal membranes of brain | Rattus norvegicus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.3 | - |
- |
Rattus norvegicus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.8 | - |
IC50: 0.8 mM | Rattus norvegicus | Ca2+ |