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Literature summary for 4.1.1.19 extracted from
- Arginine decarboxylase from a Pseudomonas species (1976), J. Bacteriol., 125, 601-607.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| agmatine | - |
Pseudomonas sp. |  |
| canavanine | L-canavanine | Pseudomonas sp. | |
| D-Arg | - |
Pseudomonas sp. | |
| EDTA | - |
Pseudomonas sp. | |
| homoarginine | - |
Pseudomonas sp. | |
| L-Lys | - |
Pseudomonas sp. | |
| N5-Hydroxy-DL-Arg | - |
Pseudomonas sp. | |
| Orn | - |
Pseudomonas sp. | |
| PCMB | dithiothreitol prevents inhibition | Pseudomonas sp. | |
| polyamines | - |
Pseudomonas sp. | |
| putrescine | - |
Pseudomonas sp. | |
| spermidine | - |
Pseudomonas sp. | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.23 | - |
L-Arg | pH 7.2 | Pseudomonas sp. | |
| 0.26 | - |
L-Arg | pH 8.1 | Pseudomonas sp. | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required | Pseudomonas sp. | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Arg | Pseudomonas sp. | constitutive enzyme | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pseudomonas sp. | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Pseudomonas sp. |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 0.113 | - |
- |
Pseudomonas sp. |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Arg | constitutive enzyme | Pseudomonas sp. | ? | - |
? | |
| L-arginine | - |
Pseudomonas sp. | agmatine + CO2 | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.1 | - |
- |
Pseudomonas sp. |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 7.2 | 8.8 | pH 7.2: about 45% of maximal activity, pH 8.8: about 35% of maximal activity | Pseudomonas sp. |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | required | Pseudomonas sp. | |
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