Application | Comment | Organism |
---|---|---|
synthesis | the enzyme can be used for synthesis of cadaverine, a biogenic amine, that has the potential to become an important platform chemical for the production of industrial polymers, such as polyamides and polyurethanes | Klebsiella oxytoca |
Cloned (Comment) | Organism |
---|---|
gene lysA, recombinant enzyme overexpression in Escherichia coli strain LN18 | Klebsiella oxytoca |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ca2+ | - |
Klebsiella oxytoca | |
Fe2+ | - |
Klebsiella oxytoca | |
Zn2+ | - |
Klebsiella oxytoca |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | activates | Klebsiella oxytoca |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-lysine | Klebsiella oxytoca | - |
cadaverine + CO2 | - |
? | |
L-lysine | Klebsiella oxytoca ATCC 8724 / DSM 4798 / JCM 20051 / NBRC 3318 / NRRL B-199 / KCTC 1686 | - |
cadaverine + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Klebsiella oxytoca | A0A0H3H393 | - |
- |
Klebsiella oxytoca ATCC 8724 / DSM 4798 / JCM 20051 / NBRC 3318 / NRRL B-199 / KCTC 1686 | A0A0H3H393 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-lysine | - |
Klebsiella oxytoca | cadaverine + CO2 | - |
? | |
L-lysine | - |
Klebsiella oxytoca ATCC 8724 / DSM 4798 / JCM 20051 / NBRC 3318 / NRRL B-199 / KCTC 1686 | cadaverine + CO2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 80000, recombinant enzyme | Klebsiella oxytoca |
Synonyms | Comment | Organism |
---|---|---|
LysA | - |
Klebsiella oxytoca |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
55 | - |
recombinant enzyme | Klebsiella oxytoca |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
5.5 | - |
recombinant enzyme | Klebsiella oxytoca |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
5.5 | 8 | maximal activity at pH 5.5, 30% of maximal activity at pH 8.0 | Klebsiella oxytoca |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Klebsiella oxytoca |