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Literature summary for 4.1.1.17 extracted from

  • Nilsson, T.; Bogdanovic, N.; Volkman, I.; Winblad, B.; Folkesson, R.; Benedikz, E.
    Altered subcellular localization of ornithine decarboxylase in Alzheimers disease brain (2006), Biochem. Biophys. Res. Commun., 344, 640-646.
    View publication on PubMed
Search for more literature for 4.1.1.17

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm altered subcellular localization of ornithine decarboxylase from nucleus to cytosol in Alzheimers disease brain, overview Homo sapiens 5737
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additional information immunohictochemic subcellular analysis of cells, overview Homo sapiens
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-ornithine Homo sapiens ODC is the initial and rate-limiting enzyme in polyamine biosynthesis putrescine + CO2
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
brain post-mortem healthy and Alzheimers disease brains, altered subcellular localization of ornithine decarboxylase in Alzheimers disease brain, overview Homo sapiens
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cerebellum
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 Homo sapiens
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hippocampus
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 Homo sapiens
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prefrontal cortex
-
 Homo sapiens
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Purkinje cell
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 Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-ornithine
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 Homo sapiens putrescine + CO2
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 ?
L-ornithine ODC is the initial and rate-limiting enzyme in polyamine biosynthesis Homo sapiens putrescine + CO2
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 ?

Synonyms

Synonyms Comment Organism
ODC
-
 Homo sapiens

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Homo sapiens