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Literature summary for 4.1.1.17 extracted from

  • Frossard, M.L.; Seabra, S.H.; DaMatta, R.A.; de Souza, W.; de Mello, F.G.; Machado Motta, M.C.
    An endosymbiont positively modulates ornithine decarboxylase in host trypanosomatids (2006), Biochem. Biophys. Res. Commun., 343, 443-449.
    View publication on PubMed

Activating Compound

Activating Compound Comment Organism Structure
additional information ODC activity is higher in endosymbiont-bearing trypanosomatids than in aposymbiotic cells, but isolated endosymbionts do not display this enzyme activity, expressed levels of ODC are similar in both strains, suggesting that ODC is positively modulated in endosymbiont-bearing cells, overview Angomonas deanei

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-ornithine Angomonas deanei ODC activity is higher in endosymbiont-bearing trypanosomatids than in aposymbiotic cells, but isolated endosymbionts do not display this enzyme activity, expressed levels of ODC are similar in both strains, suggesting that ODC is positively modulated in endosymbiont-bearing cells, overview putrescine + CO2
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?

Organism

Organism UniProt Comment Textmining
Angomonas deanei
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an endosymbiont-containing trypanosomatid
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Source Tissue

Source Tissue Comment Organism Textmining
additional information ODC activity is higher in endosymbiont-bearing trypanosomatids than in aposymbiotic cells, but isolated endosymbionts do not display this enzyme activity Angomonas deanei
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-ornithine
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Angomonas deanei putrescine + CO2
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?
L-ornithine ODC activity is higher in endosymbiont-bearing trypanosomatids than in aposymbiotic cells, but isolated endosymbionts do not display this enzyme activity, expressed levels of ODC are similar in both strains, suggesting that ODC is positively modulated in endosymbiont-bearing cells, overview Angomonas deanei putrescine + CO2
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?

Synonyms

Synonyms Comment Organism
ODC
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Angomonas deanei

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
assay at Angomonas deanei

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.2
-
assay at Angomonas deanei

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
Angomonas deanei