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Literature summary for 4.1.1.17 extracted from

  • Lee, Y.S.; Cho, Y.D.
    Mutation of cysteine-115 to alanine in Nicotiana glutinosa ornithine decarboxylase reduces enzyme activity (2001), J. Biochem. Mol. Biol., 34, 472-477.
No PubMed abstract available
Search for more literature for 4.1.1.17

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Nicotiana glutinosa

Protein Variants

Protein Variants Comment Organism
C115A 0.08% of wild-type activity Nicotiana glutinosa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.56
-
 L-ornithine
-
 Nicotiana glutinosa
1.79
-
 L-ornithine C115A mutant Nicotiana glutinosa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-ornithine Nicotiana glutinosa
-
 putrescine + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Nicotiana glutinosa Q9FPK5
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant ODC Nicotiana glutinosa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-ornithine
-
 Nicotiana glutinosa putrescine + CO2
-
 ?

Synonyms

Synonyms Comment Organism
ODC
-
 Nicotiana glutinosa

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3
-
 L-ornithine
-
 Nicotiana glutinosa

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
 Nicotiana glutinosa

pH Range

pH Minimum pH Maximum Comment Organism
6.4 8.7 approx. 20% of maximal activity at pH 6.4, approx. 50% of maximal activity at pH 8.6 Nicotiana glutinosa