Literature summary for 4.1.1.15 extracted from

McCormick, S.J.; Tunnicliff, G.
Kinetics of inactivation of glutamate decarboxylase by cysteine-specific reagents (2001), Acta Biochim. Pol., 48, 573-578.

Search for more literature for 4.1.1.15

Inhibitors

Inhibitors	Comment	Organism	Structure
5,5'-dithiobis(2-nitrobenzoate)	0.1 mM, 50.3% inhibition at pH 4.6, irreversible	Escherichia coli
Chloroacetamide	no inhibition at pH 4.6, marked inhibition at pH 6.0 or higher	Escherichia coli
HgCl2	0.01 mM, 80.1% inhibition at pH 4.6, irreversible	Escherichia coli
NEM	no inhibition at pH 4.6, marked inhibition at pH 6.0 or higher	Escherichia coli
PCMB	0.1 mM, 68.5% inhibition at pH 4.6, irreversible	Escherichia coli

Organism

Organism	UniProt	Comment	Textmining
Escherichia coli	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-Glu	-	Escherichia coli	4-Aminobutanoate + CO2	-	?

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
4	5	-	Escherichia coli

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Release 2023.1 (January 2023)