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Literature summary for 4.1.1.115 extracted from

  • Liu, D.; Wei, Y.; Liu, X.; Zhou, Y.; Jiang, L.; Yin, J.; Wang, F.; Hu, Y.; Nanjaraj Urs, A.N.; Liu, Y.; Ang, E.L.; Zhao, S.; Zhao, H.; Zhang, Y.
    Indoleacetate decarboxylase is a glycyl radical enzyme catalysing the formation of malodorant skatole (2018), Nat. Commun., 9, 4224 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.1.1.115

Crystallization (Commentary)

Crystallization (Comment) Organism
homology modeling of structure and docking of the indoleacetate substrate Tractidigestivibacter scatoligenes

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.358
-
 (1H-indol-3-yl)acetate pH 7.5, 30°C Clostridium scatologenes
0.37
-
 (1H-indol-3-yl)acetate pH 7.5, 30°C Tractidigestivibacter scatoligenes

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(1H-indol-3-yl)acetate Tractidigestivibacter scatoligenes
-
 skatole + CO2
-
 ?
(1H-indol-3-yl)acetate Clostridium scatologenes
-
 skatole + CO2
-
 ?
additional information Tractidigestivibacter scatoligenes no substrates: phenylacetate or p-hydroxyphenylacetate ?
-
 ?
additional information Clostridium scatologenes no substrates: phenylacetate or p-hydroxyphenylacetate ?
-
 ?

Organism

Organism UniProt Comment Textmining
Clostridium scatologenes A0A0E3M8P3
-
-
Tractidigestivibacter scatoligenes A0A100YXA1
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(1H-indol-3-yl)acetate
-
 Tractidigestivibacter scatoligenes skatole + CO2
-
 ?
(1H-indol-3-yl)acetate
-
 Clostridium scatologenes skatole + CO2
-
 ?
additional information no substrates: phenylacetate or p-hydroxyphenylacetate Tractidigestivibacter scatoligenes ?
-
 ?
additional information no substrates: phenylacetate or p-hydroxyphenylacetate Clostridium scatologenes ?
-
 ?

Synonyms

Synonyms Comment Organism
AUL39_03420
-
 Tractidigestivibacter scatoligenes
CSCA_1772
-
 Clostridium scatologenes

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2
-
 (1H-indol-3-yl)acetate pH 7.5, 30°C Tractidigestivibacter scatoligenes
130
-
 (1H-indol-3-yl)acetate pH 7.5, 30°C Clostridium scatologenes

General Information

General Information Comment Organism
physiological function indoleacetate decarboxylase is an O2-sensitive glycyl radical enzyme catalysing the decarboxylation of indoleacetate to form skatole as the terminal step of tryptophan fermentation in certain anaerobic bacteria Tractidigestivibacter scatoligenes
physiological function indoleacetate decarboxylase is an O2-sensitive glycyl radical enzyme catalysing the decarboxylation of indoleacetate to form skatole as the terminal step of tryptophan fermentation in certain anaerobic bacteria Clostridium scatologenes