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Literature summary for 4.1.1.108 extracted from

  • Torrens-Spence, M.P.; Pluskal, T.; Li, F.S.; Carballo, V.; Weng, J.K.
    Complete pathway elucidation and heterologous reconstitution of Rhodiola salidroside biosynthesis (2018), Mol. Plant, 11, 205-217 .
    View publication on PubMed
Search for more literature for 4.1.1.108

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Saccharomyces cerevisiae and Nicotiana benthamiana Rhodiola rosea

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-tyrosine + O2 + H2O Rhodiola rosea highest catalytic efficiency (4-hydroxyphenyl)acetaldehyde + CO2 + NH3 + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Rhodiola rosea
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
root
-
 Rhodiola rosea
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-3,4-dihydroxyphenylalanine + O2 + H2O
-
 Rhodiola rosea (3,4-dihydroxyphenyl)acetaldehyde + CO2 + NH3 + H2O2
-
 ?
L-phenylalanine + O2 + H2O
-
 Rhodiola rosea phenylacetaldehyde + CO2 + NH3 + H2O2
-
 ?
L-tryptophan + O2 + H2O
-
 Rhodiola rosea ?
-
 ?
L-tyrosine + O2 + H2O highest catalytic efficiency Rhodiola rosea (4-hydroxyphenyl)acetaldehyde + CO2 + NH3 + H2O2
-
 ?

Synonyms

Synonyms Comment Organism
4-HPAA synthase
-
 Rhodiola rosea
4HPAAS
-
 Rhodiola rosea

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Rhodiola rosea

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
9.1
-
 L-3,4-dihydroxyphenylalanine at pH 8.0 and 30°C Rhodiola rosea
11.7
-
 L-tyrosine at pH 8.0 and 30°C Rhodiola rosea