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Literature summary for 4.1.1.105 extracted from
- Experimental evidence and in silico identification of tryptophan decarboxylase in Citrus genus (2017), Molecules, 22, pii: E272 .
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| gene tdc, DNA and amino acid sequence determination and analysis, TDC is a homodimer and its polypeptide chain is encoded by a single copy gene without introns, sequence comparisons and phylogenetic tree | Citrus sinensis |
| gene tdc, DNA and amino acid sequence determination and analysis, TDC is a homodimer and its polypeptide chain is encoded by a single copy gene without introns, sequence comparisons and phylogenetic tree | Citrus clementina |
| gene tdc, TDC is a homodimer and its polypeptide chain is encoded by a single copy gene without introns, sequence comparisons | Citrus limon |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-tryptophan | Citrus sinensis | - |
tryptamine + CO2 | - |
? |  |
| L-tryptophan | Citrus limon | - |
tryptamine + CO2 | - |
? | |
| L-tryptophan | Citrus clementina | - |
tryptamine + CO2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Citrus clementina | - |
- |
- |
| Citrus limon | - |
- |
- |
| Citrus sinensis | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leaf | - |
Citrus sinensis | - |
| leaf | - |
Citrus limon | - |
| leaf | - |
Citrus clementina | - |
| seedling | - |
Citrus sinensis | - |
| seedling | - |
Citrus limon | - |
| seedling | - |
Citrus clementina | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-tryptophan | - |
Citrus sinensis | tryptamine + CO2 | - |
? | |
| L-tryptophan | - |
Citrus limon | tryptamine + CO2 | - |
? | |
| L-tryptophan | - |
Citrus clementina | tryptamine + CO2 | - |
? | |
| additional information | enzyme TDC has substrate specificity for Trp, but not for phenolic L-amino acids (Phe and Tyr) and their derivatives, substrate binding site sequence determination | Citrus sinensis | ? | - |
? | |
| additional information | enzyme TDC has substrate specificity for Trp, but not for phenolic L-amino acids (Phe and Tyr) and their derivatives, substrate binding site sequence determination | Citrus limon | ? | - |
? | |
| additional information | enzyme TDC has substrate specificity for Trp, but not for phenolic L-amino acids (Phe and Tyr) and their derivatives, substrate binding site sequence determination | Citrus clementina | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| TDC | - |
Citrus sinensis |
| TDC | - |
Citrus limon |
| TDC | - |
Citrus clementina |
| Tryptophan decarboxylase | - |
Citrus sinensis |
| Tryptophan decarboxylase | - |
Citrus limon |
| Tryptophan decarboxylase | - |
Citrus clementina |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Citrus sinensis |
| 37 | - |
assay at | Citrus limon |
| 37 | - |
assay at | Citrus clementina |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5 | 7.5 | assay at | Citrus sinensis |
| 5 | 7.5 | assay at | Citrus limon |
| 5 | 7.5 | assay at | Citrus clementina |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Citrus sinensis | |
| pyridoxal 5'-phosphate | - |
Citrus limon | |
| pyridoxal 5'-phosphate | - |
Citrus clementina | |
General Information
| General Information | Comment | Organism |
|---|---|---|
| metabolism | plant tryptophan decarboxylase (TDC) converts tryptophan into tryptamine, precursor of indolealkylamine alkaloids. Successive methylation pathway of the tryptamine to N,N,N-trimethyltryptamine produced from the tryptophan decarboxylation, overview | Citrus sinensis |
| metabolism | plant tryptophan decarboxylase (TDC) converts tryptophan into tryptamine, precursor of indolealkylamine alkaloids. Successive methylation pathway of the tryptamine to N,N,N-trimethyltryptamine produced from the tryptophan decarboxylation, overview | Citrus limon |
| metabolism | plant tryptophan decarboxylase (TDC) converts tryptophan into tryptamine, precursor of indolealkylamine alkaloids. Successive methylation pathway of the tryptamine to N,N,N-trimethyltryptamine produced from the tryptophan decarboxylation, overview | Citrus clementina |
| physiological function | plant tryptophan decarboxylase (TDC) converts tryptophan into tryptamine, precursor of indolealkylamine alkaloids | Citrus sinensis |
| physiological function | plant tryptophan decarboxylase (TDC) converts tryptophan into tryptamine, precursor of indolealkylamine alkaloids | Citrus limon |
| physiological function | plant tryptophan decarboxylase (TDC) converts tryptophan into tryptamine, precursor of indolealkylamine alkaloids | Citrus clementina |
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