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Literature summary for 4.1.1.1 extracted from

  • Kannuchamy, S.; Mukund, N.; Saleena, L.M.
    Genetic engineering of Clostridium thermocellum DSM1313 for enhanced ethanol production (2016), BMC Biotechnol., 16, 34.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
synthesis enhancement of ethanol production capacity of Clostridium thermocellum by transferring pyruvate decarboxylase and alcohol dehydrogenase genes of the homoethanol pathway from Zymomonas mobilis. Both transferring pyruvate decarboxylase and alcohol dehydrogenase are functional in Clostridium thermocellum, but the presence of and alcohol dehydrogenase severely limits the growth of the recombinant strains, irrespective of the presence or absence of the pyruvate decarboxylase gene. The recombinant strain shows two-fold increase in pyruvate carboxylase activity and ethanol production when compared with the wild type strain Zymomonas mobilis

Cloned(Commentary)

Cloned (Comment) Organism
expression in Clostridium thermocellum Zymomonas mobilis

Organism

Organism UniProt Comment Textmining
Zymomonas mobilis D9J047
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