Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | no substrate activation, PDC activity is regulated in response to growth substrate, highest with lactic acid, lower with ethanol or glycerol, and absent with mannitol | Acetobacter pasteurianus |
Cloned (Comment) | Organism |
---|---|
expression of pdc gene in recombinant Escherichia coli, sequencing, pdc operon | Acetobacter pasteurianus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | cofactor | Acetobacter pasteurianus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
58873 | - |
x * 58873, anhydrous molecular mass, calculated from the amino acid sequence | Acetobacter pasteurianus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
pyruvate | Acetobacter pasteurianus | key enzyme for the oxidative metabolism of lactic acid | acetaldehyde + CO2 | - |
? | |
pyruvate | Acetobacter pasteurianus NCIB 8618 / ATCC 12874 | key enzyme for the oxidative metabolism of lactic acid | acetaldehyde + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Acetobacter pasteurianus | Q8L388 | - |
- |
Acetobacter pasteurianus NCIB 8618 / ATCC 12874 | Q8L388 | - |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
- |
Acetobacter pasteurianus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
pyruvate | - |
Acetobacter pasteurianus | acetaldehyde + CO2 | - |
? | |
pyruvate | key enzyme for the oxidative metabolism of lactic acid | Acetobacter pasteurianus | acetaldehyde + CO2 | - |
? | |
pyruvate | - |
Acetobacter pasteurianus NCIB 8618 / ATCC 12874 | acetaldehyde + CO2 | - |
? | |
pyruvate | key enzyme for the oxidative metabolism of lactic acid | Acetobacter pasteurianus NCIB 8618 / ATCC 12874 | acetaldehyde + CO2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 58873, anhydrous molecular mass, calculated from the amino acid sequence | Acetobacter pasteurianus |
Synonyms | Comment | Organism |
---|---|---|
PDC | - |
Acetobacter pasteurianus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
thiamine diphosphate | - |
Acetobacter pasteurianus |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Acetobacter pasteurianus | calculated from the amino acid sequence | - |
5.49 |