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Literature summary for 3.9.1.3 extracted from

  • Seeger, A.; Rose, K.; Ma, N.T.; Kremmer, E.; Klumpp, S.; Krieglstein, J.
    Influence of protein histidine phosphatase overexpression and down-regulation on human umbilical-vein endothelial cell viability (2012), Cell Biol. Int., 36, 245-249.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
H53A inactive Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
cytosol
-
Homo sapiens 5829
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
13700
-
1 * 13700, calculated from amino acid sequence Homo sapiens
16300
-
1 * 16300, recombinant enzyme, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
a [protein]-N-phospho-L-histidine + H2O Homo sapiens
-
a [protein]-L-histidine + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9NRX4
-
-

Source Tissue

Source Tissue Comment Organism Textmining
SH-SY5Y cell
-
Homo sapiens
-
SN-56 cell
-
Homo sapiens
-
umbilical vein endothelial cell
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
a [protein]-N-phospho-L-histidine + H2O
-
Homo sapiens a [protein]-L-histidine + phosphate
-
?

Subunits

Subunits Comment Organism
monomer 1 * 13700, calculated from amino acid sequence Homo sapiens
monomer 1 * 16300, recombinant enzyme, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
PHP
-
Homo sapiens
protein histidine phosphatase
-
Homo sapiens

General Information

General Information Comment Organism
physiological function enzyme overexpression induces apoptosis in umbilical-vein endothelial cells Homo sapiens