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Literature summary for 3.8.1.5 extracted from
- Phylogenetic analysis of haloalkane dehalogenases (2007), Proteins, 67, 305-316.
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-haloalkane + H2O | Mycobacterium avium | subfamily HLD-I, substrates small, terminally halogenated | a primary alcohol + halide | - |
? |  |
| 1-haloalkane + H2O | Mycobacterium tuberculosis | subfamily HLD-I, substrates small, terminally halogenated | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | Xanthobacter autotrophicus | subfamily HLD-I, substrates small, terminally halogenated | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | Mycolicibacterium smegmatis | subfamily HLD-II, substrates larger, beta-substituted | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | Mycobacterium tuberculosis | subfamily HLD-II, substrates larger, beta-substituted | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | Sphingobium indicum | subfamily HLD-II, substrates larger, beta-substituted | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | Rhodococcus sp. | subfamily HLD-II, substrates larger, beta-substituted | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | Bradyrhizobium japonicum | subfamily HLD-II, substrates larger, beta-substituted | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | Mesorhizobium loti | subfamily HLD-II, substrates larger, beta-substituted | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | Agrobacterium tumefaciens | subfamily HLD-II, substrates larger, beta-substituted | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | Mycobacterium tuberculosis | subfamily HLD-III, unknown substrates | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | Rhodopirellula baltica | subfamily HLD-III, unknown substrates | a primary alcohol + halide | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Agrobacterium tumefaciens | Q8U671 | - |
- |
| Bradyrhizobium japonicum | P59337 | - |
- |
| Mesorhizobium loti | Q98C03 | - |
- |
| Mycobacterium avium | - |
- |
- |
| Mycobacterium tuberculosis | - |
- |
- |
| Mycolicibacterium smegmatis | - |
- |
- |
| Rhodococcus sp. | P0A3G3 | - |
- |
| Rhodopirellula baltica | Q7UF99 | - |
- |
| Sphingobium indicum | A8CFB7 | - |
- |
| Xanthobacter autotrophicus | P22643 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-haloalkane + H2O | subfamily HLD-I, substrates small, terminally halogenated | Mycobacterium avium | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | subfamily HLD-I, substrates small, terminally halogenated | Mycobacterium tuberculosis | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | subfamily HLD-I, substrates small, terminally halogenated | Xanthobacter autotrophicus | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | subfamily HLD-II, substrates larger, beta-substituted | Mycolicibacterium smegmatis | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | subfamily HLD-II, substrates larger, beta-substituted | Mycobacterium tuberculosis | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | subfamily HLD-II, substrates larger, beta-substituted | Sphingobium indicum | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | subfamily HLD-II, substrates larger, beta-substituted | Rhodococcus sp. | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | subfamily HLD-II, substrates larger, beta-substituted | Bradyrhizobium japonicum | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | subfamily HLD-II, substrates larger, beta-substituted | Mesorhizobium loti | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | subfamily HLD-II, substrates larger, beta-substituted | Agrobacterium tumefaciens | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | subfamily HLD-III, unknown substrates | Mycobacterium tuberculosis | a primary alcohol + halide | - |
? | |
| 1-haloalkane + H2O | subfamily HLD-III, unknown substrates | Rhodopirellula baltica | a primary alcohol + halide | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DatA | phylogenetic analysis, subfamily HLD-II | Agrobacterium tumefaciens |
| DbjA | phylogenetic analysis, subfamily HLD-II | Bradyrhizobium japonicum |
| DhaA | phylogenetic analysis, subfamily HLD-II | Rhodococcus sp. |
| DhlA | phylogenetic analysis, subfamily HLD-I | Xanthobacter autotrophicus |
| DhmA | phylogenetic analysis, subfamily HLD-I | Mycobacterium avium |
| dmbA | phylogenetic analysis, subfamily HLD-II | Mycobacterium tuberculosis |
| DmbB | phylogenetic analysis, subfamily HLD-I | Mycobacterium tuberculosis |
| DmbC | phylogenetic analysis, subfamily HLD-III | Mycobacterium tuberculosis |
| dmlA | phylogenetic analysis, subfamily HLD-II | Mesorhizobium loti |
| DmsA | phylogenetic analysis, subfamily HLD-II | Mycolicibacterium smegmatis |
| DrbA | phylogenetic analysis, subfamily HLD-III | Rhodopirellula baltica |
| haloalkane dehalogenase | - |
Mycolicibacterium smegmatis |
| haloalkane dehalogenase | - |
Mycobacterium avium |
| haloalkane dehalogenase | - |
Mycobacterium tuberculosis |
| haloalkane dehalogenase | - |
Sphingobium indicum |
| haloalkane dehalogenase | - |
Rhodococcus sp. |
| haloalkane dehalogenase | - |
Xanthobacter autotrophicus |
| haloalkane dehalogenase | - |
Bradyrhizobium japonicum |
| haloalkane dehalogenase | - |
Mesorhizobium loti |
| haloalkane dehalogenase | - |
Agrobacterium tumefaciens |
| haloalkane dehalogenase | - |
Rhodopirellula baltica |
| LinB | phylogenetic analysis, subfamily HLD-II | Sphingobium indicum |
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