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Literature summary for 3.8.1.5 extracted from

  • Silberstein, M.; Damborsky, J.; Vajda, S.
    Exploring the binding sites of the haloalkane dehalogenase DhlA from Xanthobacter autotrophicus GJ10 (2007), Biochemistry, 46, 9239-9249.
    View publication on PubMed

Application

Application Comment Organism
environmental protection because the halogenated substrates are often environmentally toxic industrial byproducts, the enzyme has been suggested to be an useful catalyst for biodegradation and bioremediation Sphingomonas paucimobilis
environmental protection because the halogenated substrates are often environmentally toxic industrial byproducts, the enzyme has been suggested to be an useful catalyst for biodegradation and bioremediation Rhodococcus sp.
environmental protection because the halogenated substrates are often environmentally toxic industrial byproducts, the enzyme has been suggested to be an useful catalyst for biodegradation and bioremediation Xanthobacter autotrophicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1,2-dichloroethane + H2O Xanthobacter autotrophicus
-
2-chloroethanol + chloride
-
?
1-haloalkane + H2O Sphingomonas paucimobilis
-
a primary alcohol + halide
-
?
1-haloalkane + H2O Rhodococcus sp.
-
a primary alcohol + halide
-
?

Organism

Organism UniProt Comment Textmining
Rhodococcus sp. P0A3G3
-
-
Sphingomonas paucimobilis P51698
-
-
Xanthobacter autotrophicus P22643
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,2-dichloroethane + H2O
-
Xanthobacter autotrophicus 2-chloroethanol + chloride
-
?
1-haloalkane + H2O
-
Sphingomonas paucimobilis a primary alcohol + halide
-
?
1-haloalkane + H2O
-
Rhodococcus sp. a primary alcohol + halide
-
?

Synonyms

Synonyms Comment Organism
DhaA
-
Rhodococcus sp.
DhlA
-
Xanthobacter autotrophicus
haloalkane dehalogenase
-
Sphingomonas paucimobilis
haloalkane dehalogenase
-
Rhodococcus sp.
haloalkane dehalogenase
-
Xanthobacter autotrophicus
LinB
-
Sphingomonas paucimobilis