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Literature summary for 3.8.1.11 extracted from

  • Weightman, A.J.; Weightman, A.L.; Slater, J.H.
    Stereospecificity of 2-monochloropropionate dehalogenation by the two dehalogenases of Pseudomonas P3: evidence for two different dehalogenation mechanisms (1982), J. Gen. Microbiol., 128, 1755-1762.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
N-ethylmaleimide dithiothreitol partially protects from inhibition Pseudomonas putida
p-chloromercuribenzoate
-
Pseudomonas putida

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(R)-2-haloacid + H2O Pseudomonas putida
-
(R)-2-hydroxyacid + halide
-
?
(R)-2-haloacid + H2O Pseudomonas putida PP3
-
(R)-2-hydroxyacid + halide
-
?
(S)-2-haloacid + H2O Pseudomonas putida
-
(S)-2-hydroxyacid + halide
-
?
(S)-2-haloacid + H2O Pseudomonas putida PP3
-
(S)-2-hydroxyacid + halide
-
?

Organism

Organism UniProt Comment Textmining
Pseudomonas putida
-
PP3
-
Pseudomonas putida PP3
-
PP3
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(R)-2-haloacid + H2O
-
Pseudomonas putida (R)-2-hydroxyacid + halide
-
?
(R)-2-haloacid + H2O
-
Pseudomonas putida PP3 (R)-2-hydroxyacid + halide
-
?
(S)-2-haloacid + H2O
-
Pseudomonas putida (S)-2-hydroxyacid + halide
-
?
(S)-2-haloacid + H2O
-
Pseudomonas putida PP3 (S)-2-hydroxyacid + halide
-
?