Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-2-chloropropionic acid + H2O | Pseudomonas sp. | - |
(S)-2-hydroxypropionic acid + chloride | - |
? | |
(R)-2-chloropropionic acid + H2O | Pseudomonas sp. 113 | - |
(S)-2-hydroxypropionic acid + chloride | - |
? | |
(S)-2-chloropropionic acid + H2O | Pseudomonas sp. | - |
(R)-2-hydroxypropionic acid + chloride | - |
? | |
(S)-2-chloropropionic acid + H2O | Pseudomonas sp. 113 | - |
(R)-2-hydroxypropionic acid + chloride | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Pseudomonas sp. | - |
- |
- |
Pseudomonas sp. 113 | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-2-chloropropionic acid + H2O | - |
Pseudomonas sp. | (S)-2-hydroxypropionic acid + chloride | - |
? | |
(R)-2-chloropropionic acid + H2O | - |
Pseudomonas sp. 113 | (S)-2-hydroxypropionic acid + chloride | - |
? | |
(S)-2-chloropropionic acid + H2O | - |
Pseudomonas sp. | (R)-2-hydroxypropionic acid + chloride | - |
? | |
(S)-2-chloropropionic acid + H2O | - |
Pseudomonas sp. 113 | (R)-2-hydroxypropionic acid + chloride | - |
? | |
additional information | the enzyme has a single common active site for both reactions on L- and D-enantiomers, the reaction mechanismm does not proceed via an ester intermediate and not via a nucleophilic aspartate attacking the C-atom of the substrate to displace the halo-atom on contrast to the (S)-2-haloacid dehalogenase, EC 3.8.1.2. In the (S,R)-2-haloacid dehalogenase, a water molecule directly atacks the substrate for halide displacement, structure-function relationship, overview | Pseudomonas sp. | ? | - |
? | |
additional information | the enzyme has a single common active site for both reactions on L- and D-enantiomers, the reaction mechanismm does not proceed via an ester intermediate and not via a nucleophilic aspartate attacking the C-atom of the substrate to displace the halo-atom on contrast to the (S)-2-haloacid dehalogenase, EC 3.8.1.2. In the (S,R)-2-haloacid dehalogenase, a water molecule directly atacks the substrate for halide displacement, structure-function relationship, overview | Pseudomonas sp. 113 | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | structure comparisons, overview | Pseudomonas sp. |
Synonyms | Comment | Organism |
---|---|---|
DL-2-haloacid dehalogenase | - |
Pseudomonas sp. |
DL-DEX 113 | - |
Pseudomonas sp. |