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Literature summary for 3.7.1.8 extracted from

  • Ahmad, S.; Fraser, J.; Sylvestre, M.; Larose, A.; Khan, A.; Bergeron, J.; Juteau, J.M.; Sondossi, M.
    Sequence of the bphD gene encoding 2-hydroxy-6-oxo-(phenylchlorophenyl) hexa-2,4-dienoic acid (HOP/cPCA) hydrolase involved in the biphenyl/polychlorinated biphenyl degradation pathway in Comamonas testosteroni: evidence suggesting involvement of Ser112 in catalytic activity (1995), Gene, 156, 69-74.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Comamonas testosteroni

Protein Variants

Protein Variants Comment Organism
S112A inactive enzyme Comamonas testosteroni

Inhibitors

Inhibitors Comment Organism Structure
PMSF inhibition of semipurified enzyme Comamonas testosteroni

Organism

Organism UniProt Comment Textmining
Comamonas testosteroni Q59324
-
-

Reaction

Reaction Comment Organism Reaction ID
2,6-dioxo-6-phenylhexa-3-enoate + H2O = benzoate + 2-oxopent-4-enoate mechanism may involve an Asp-Ser-His catalytic triad Comamonas testosteroni