Literature summary for 3.7.1.4 extracted from

Diekmann, L.; Behrendt, M.; Amiri, M.; Naim, H.Y.
Structural determinants for transport of lactase phlorizin-hydrolase in the early secretory pathway as a multi-domain membrane glycoprotein (2017), Biochim. Biophys. Acta, 1861, 3119-3128 .

Search for more literature for 3.7.1.4

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in COS-1 cells	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
N1340Q	the variant lacks the closest potential N-glycosylation site to Asp1338	Homo sapiens
N1814Q	the variant lacks the N-glycosylation site in the domain IV	Homo sapiens
N821Q	the variant lacks the N-glycosylation site in the domain II	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
membrane	-	Homo sapiens	16020	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
250000	-	gel filtration	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Posttranslational Modification

Posttranslational Modification	Comment	Organism
glycoprotein	-	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
intestinal epithelium	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
lactose + H2O	-	Homo sapiens	D-galactose + D-glucose	-	?
phlorhizin + H2O	-	Homo sapiens	3-(4-hydroxyphenyl)propanoate + arbutin	-	?

Subunits

Subunits	Comment	Organism
homodimer	-	Homo sapiens

Synonyms

Synonyms	Comment	Organism
lactase phlorizin-hydrolase	-	Homo sapiens
LPH	-	Homo sapiens

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)