Literature summary for 3.7.1.3 extracted from

Cyr, L.V.; Newton, M.G.; Phillips, R.S
Stereospecificity of Pseudomonas fluorescens kynureninase for diastereomers of beta-methylkynurenine (1999), Bioorg. Med. Chem., 7, 1497-1503.

Search for more literature for 3.7.1.3

Application

Application	Comment	Organism
medicine	NAD+ biosynthesis	Pseudomonas fluorescens
medicine	tryptophan metabolism	Pseudomonas fluorescens

Inhibitors

Inhibitors	Comment	Organism	Structure
(4S)-dihydro-L-kynurenine	-	Pseudomonas fluorescens
S-(2-aminophenyl)-L-cysteine S,S-dioxide	-	Pseudomonas fluorescens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
3-hydroxy-L-kynurenine + H2O	Pseudomonas fluorescens	-	3-hydroxyanthranilate + L-Ala	-	?
L-kynurenine + H2O	Pseudomonas fluorescens	-	anthranilate + L-alanine	-	?

Organism

Organism	UniProt	Comment	Textmining
Pseudomonas fluorescens	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
(2S,3S)-erythro-beta-methyl-L-kynurenine	-	Pseudomonas fluorescens	?	-	?
(4R)-dihydro-L-kynurenine + H2O	-	Pseudomonas fluorescens	2-aminobenzaldehyde + L-alanine	-	?
3-hydroxy-L-kynurenine + H2O	-	Pseudomonas fluorescens	3-hydroxyanthranilate + L-alanine	-	?
3-hydroxy-L-kynurenine + H2O	-	Pseudomonas fluorescens	3-hydroxyanthranilate + L-Ala	-	?
L-kynurenine + H2O	-	Pseudomonas fluorescens	anthranilate + L-alanine	-	?

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Release 2023.1 (January 2023)