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Literature summary for 3.7.1.3 extracted from

  • Wiss, O.; Weber, F.
    Die Reindarstellung der Kynureninase (1956), Hoppe-Seyler's Z. Physiol. Chem., 304, 232-240.
No PubMed abstract available

Application

Application Comment Organism
medicine tryptophan metabolism Sus scrofa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-hydroxy-L-kynurenine + H2O Sus scrofa
-
3-hydroxyanthranilate + L-Ala
-
?
L-kynurenine + H2O Sus scrofa
-
anthranilate + L-alanine
-
?

Organism

Organism UniProt Comment Textmining
Sus scrofa
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Sus scrofa

Source Tissue

Source Tissue Comment Organism Textmining
liver
-
Sus scrofa
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
68.3
-
-
Sus scrofa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-hydroxy-L-kynurenine + H2O
-
Sus scrofa 3-hydroxyanthranilate + L-alanine
-
?
3-hydroxy-L-kynurenine + H2O
-
Sus scrofa 3-hydroxyanthranilate + L-Ala
-
?
L-kynurenine + H2O
-
Sus scrofa anthranilate + L-alanine
-
?

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
Sus scrofa
vitamin B6
-
Sus scrofa