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Literature summary for 3.6.5.5 extracted from

  • Hamao, K.; Morita, M.; Hosoya, H.
    New function of the proline rich domain in dynamin-2 to negatively regulate its interaction with microtubules in mammalian cells (2009), Exp. Cell Res., 315, 1336-1345.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HeLa cells Rattus norvegicus

Protein Variants

Protein Variants Comment Organism
K44A mutant with reduced the GTP binding affinity and therefore impaired the GTPase activity Rattus norvegicus
additional information GFP-dynamin-2-(1-786), a truncated mutant lacking a C-terminal portion of the proline rich domain, localizes along microtubules in interphase HeLa cells Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microtubule dynamin along microtubules is only observed at the spindle midzone during mitosis but not in interphase cells Rattus norvegicus 5874
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus P39052
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Synonyms

Synonyms Comment Organism
dynamin-2
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Rattus norvegicus