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Literature summary for 3.6.5.5 extracted from

  • Tang, D.; Ade, J.; Frye, C.A.; Innes, R.W.
    A mutation in the GTP hydrolysis site of Arabidopsis dynamin-related protein 1E confers enhanced cell death in response to powdery mildew infection (2006), Plant J., 47, 75-84.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
agriculture the edr3 mutant displays enhanced disease resistance to Erysiphe cichoracearum and enhanced susceptibility to Botrytis cinerea Arabidopsis thaliana

Cloned(Commentary)

Cloned (Comment) Organism
for identification of the EDR3 gene a cosmid library using BAC F27H5 DNA is constructed, for investigation of the subcellular localization a green fluorescent protein fusion to the N-terminus of DRP1E is used Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
P77L edr3 mutant, GTP hydrolysis is blocked, but not GTP binding Arabidopsis thaliana

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
Arabidopsis thaliana 5739
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
69800
-
predicted molecular mass Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + H2O Arabidopsis thaliana
-
GDP + phosphate
-
ir

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
root
-
Arabidopsis thaliana
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + H2O
-
Arabidopsis thaliana GDP + phosphate
-
ir

Synonyms

Synonyms Comment Organism
DRP1E
-
Arabidopsis thaliana
dynamin-related protein 1E
-
Arabidopsis thaliana

pI Value

Organism Comment pI Value Maximum pI Value
Arabidopsis thaliana predicted pI-value
-
7.5