Application | Comment | Organism |
---|---|---|
medicine | dynamin-1 interacts with TULP1, TULP1 is a photoreceptor-specific protein that is mutated in retinitis pigmentosa | Mus musculus |
Cloned (Comment) | Organism |
---|---|
the full-length mouse dynamin-1 cDNA isolated from retina is subcloned into the pGEX-2TK vector, the construct is used to generate three different dynamin-1 domain constructs, the N-terminal domain, aa 1-520, the proline-rich domain, aa 750-814, and the C-terminal domain, aa 521-814 | Mus musculus |
Protein Variants | Comment | Organism |
---|---|---|
GST-Dyn1-C | single domain of dynamin-1, constructed for the identification of the interaction domains between dynamin-1 and TULP1 | Mus musculus |
GST-Dyn1-N | single domain of dynamin-1, constructed for the identification of the interaction domains between dynamin-1 and TULP1 | Mus musculus |
GST-Dyn1-PRD | single domain of dynamin-1, constructed for the identification of the interaction domains between dynamin-1 and TULP1 | Mus musculus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
95000 | - |
identified in immunoprecipitation experiments by MS/MS sequence analysis | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | Mus musculus | - |
GDP + phosphate | - |
ir |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
glutathione S-transferase dynamin-1 fusion constructs are expressed in Escherichia coli BL21 cells, the proteins are purified using glutathione-Sepharose 4B beads | Mus musculus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
outer plexiform layer | - |
Mus musculus | - |
photoreceptor | photoreceptor cell | Mus musculus | - |
retina | - |
Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | - |
Mus musculus | GDP + phosphate | - |
ir |
Synonyms | Comment | Organism |
---|---|---|
dynamin GTPase | - |
Mus musculus |
dynamin-1 | - |
Mus musculus |
GTPase dynamin-1 | - |
Mus musculus |