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Literature summary for 3.6.5.5 extracted from

  • Lin, H.C.; Gilman, A.G.
    Regulation of dynamin I GTPase activity by G protein betagamma subunits and phosphatidylinositol 4,5-bisphosphate (1996), J. Biol. Chem., 271, 27979-27982.
    View publication on PubMed
Search for more literature for 3.6.5.5

Activating Compound

Activating Compound Comment Organism Structure
phosphatidylinositol-4,5-bisphosphate activates Homo sapiens
phosphatidylinositol-4,5-bisphosphate activates Bos taurus

Inhibitors

Inhibitors Comment Organism Structure
heterotrimeric G protein betagamma subunit complex oligomerization of dynamin prevents inhibition Bos taurus
heterotrimeric G protein betagamma subunit complex oligomerization of dynamin prevents inhibition Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + H2O Homo sapiens critical step in fission of coated pits to form coated vesicles GDP + phosphate
-
 ?
GTP + H2O Bos taurus critical step in fission of coated pits to form coated vesicles GDP + phosphate
-
 ?
GTP + H2O Homo sapiens plays an essential role in synaptic vesicle recycling GDP + phosphate
-
 ?
GTP + H2O Bos taurus plays an essential role in synaptic vesicle recycling GDP + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Homo sapiens
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Homo sapiens
-
 Bos taurus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Bos taurus
-
additional information SF-9 cells infected with recombinant baculovirus encoding human dynamin I Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + H2O
-
 Homo sapiens GDP + phosphate
-
 ?
GTP + H2O
-
 Bos taurus GDP + phosphate
-
 ?
GTP + H2O critical step in fission of coated pits to form coated vesicles Homo sapiens GDP + phosphate
-
 ?
GTP + H2O critical step in fission of coated pits to form coated vesicles Bos taurus GDP + phosphate
-
 ?
GTP + H2O plays an essential role in synaptic vesicle recycling Homo sapiens GDP + phosphate
-
 ?
GTP + H2O plays an essential role in synaptic vesicle recycling Bos taurus GDP + phosphate
-
 ?