Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | ribosomes lacking the 23S rRNA and with deletion of SRL region, but not of GAC, inactivate EF-G1 | Thermus aquaticus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Mg2+ | required | Thermus aquaticus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | Thermus aquaticus | - |
GDP + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Thermus aquaticus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | - |
Thermus aquaticus | GDP + phosphate | - |
? | |
GTP + H2O | Base A 2660 is crucial for GTPase activity of EF-G. Reaction rates using reconstituted ribosomes, single turnover measurement, overview | Thermus aquaticus | GDP + phosphate | - |
? |
Synonyms | Comment | Organism |
---|---|---|
EF-G GTPase | - |
Thermus aquaticus |
EF-G1 | - |
Thermus aquaticus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Thermus aquaticus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Thermus aquaticus |
General Information | Comment | Organism |
---|---|---|
physiological function | the EF-G GTPase mediates the movement of the tRNA2-mRNA complex during translation | Thermus aquaticus |